Bernardino, the son of Pierantonio Mezzastris, was first documented in 1502.  He was a young man at that point, probably working in his father’s workshop.  He emerges as an independent artist only after his father’s death in 1506.

Two signed frescos (see below) are known:

1. ✴the Madonna and Child with saints (1507) in Sant’ Illuminata, Montefalco; and
   

2. ✴Madonna and Child with saints (1533) in the now-closed Chiesa Tonda, Spello.
   

Foligno

St Amicus (1508)

Crucifixion (1525)

St Roch (16th century)

Frescoes (16th century)

These frescoes in San Giovanni Battista, which are attributed to Bernardino Mezzastris, depict:

1. ✴the Madonna and Child enthroned with SS Antony of Padua and Felicianus; and
   

2. ✴the Crucifixion (damaged).
   

Madonna and Child with saints (16th century)

This damaged fresco in San Domenico (in the left apsidal chapel), which is attributed to Bernardino Mezzastris, depicts the Madonna and Child enthroned with St John the Baptist and other saints and angels.

Bevagna

Madonna and Child with saints (16th century)

This fresco in Sant’ Agostino (in a niche in the right wall), which is attributed to Bernardino Mezzastris, depicts the Madonna and Child enthroned with SS Andrew and Nicholas of Tolentino and musical angels.

Montefalco

Frescoes (1507)

1. ✴the Madonna and Child enthroned;
   

2. ✴SS Roch, Sebastian, Nicholas of Tolentino and Augustine, on the left;
   

3. ✴St Clare of Montefalco, Blessed Joanna and SS Catherine of Alexandria and Illuminata, on the right; and
   

4. ✴angels throwing flowers, in the dome.
   

Painted niche (1529)

Spello

Madonna and Child with saints (1533)

This fresco, which is signed by Bernardino Mezzastris and dated by inscription, was in the now-closed Chiesa Tonda (in the niche on the left in the apse).  It depicted the Madonna and Child with SS Anna, Joseph and Michael.

Spoleto

Crucifixion (16th century)

This damaged fresco high up in the apse of San Salvatore, which is attributed to Bernardino Mezzastris, depicts the Crucifixion with;

1. ✴St John the Baptist and the Virgin, on the left and
   

2. ✴SS John the Evangelist and Senzius,who spears a green dragon, on the right.