Nothing is known about the early history of this small church and nunnery, which stand on foundations provided by the inner walls of Trevi. It is documented in 1385 as "San Bartolomeo o dei sacchi", suggesting that the nuns followed a rule of poverty and were thus probably Poor Clares.
The complex was in private hands in 1495, when a small community of women managed to acquire it and reinstate it as a nunnery. They established an orphanage here in 1796, and this subsequently became a secular institution.
The complex was subsequently adapted to form apartments.
Two frescoes survive: